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Liverpool Women's Hospital
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Freedom of Information curve
  Crown Street
Liverpool, L8 7SS
Tel: tel:0151 708 9988
Fax: 0151 702 4028

Freezing and Storage of Embryos

When you first visit the Unit to discuss your future treatment, the Doctor will discuss with you the possibility of embryo freezing. During IVF or ICSI , ‘extra’ embryos may be produced. With your consent these can be disposed of, or they may be frozen for your future treatment.

What is involved in embryo freezing
The freezing (also known as cryopreservation) of ‘extra’ embryos involves cooling them and storing them at very low temperatures. This technique enables us to keep ‘extra’ embryos as best as we can.

What are the advantages of storing embryos?

The benefit of storing ‘extra’ embryos is that you will be able to undergo subsequent replacement of embryos without having to undergo ovarian stimulation and egg collection.

What are the disadvantages of storing embryos?
Approximately 30 % of embryos do not survive the freeze-thaw process and occasionally all the embryos from one patient may fail to survive. Another disadvantage is that there is no guarantee that when the embryos are replaced they will implant. Pregnancy rates are generally less than those following fresh embryo transfer.

How long can embryos be stored for?

Embryos can be stored for years but the normal maximum statutory period under the 1990 Human Fertilisation & Embryology Act is five years. This storage period may be extended under the following circumstances where the woman being treated, or her partner (if he provided the sperm):-

(a) Is likely to develop ‘significantly impaired’ infertillity
(b) Carry a significant gene defect
(c) Become ‘prematurely and completely’ infertile

For (a) and (b), the maximum statutory storage period depends upon the age of the woman at the time the embryos were stored. If she is 45 years or under at the time the embryos were first stored, the period is 10 years. However, if the woman is 46 years or over at the time the embryos were stored, the period is determined by the date the woman being treated becomes 55.

For (c) the maximum storage period can be more than 10 years. However, supporting clinical judgement must be provided in writing, by two doctors (one independent of the unit) who are familiar with the woman and her treatment or partner, their condition and medical history.

The man and the woman whose sperm and eggs were used to produce the embryos must confirm in writing that they have no objection to the embryos being stored for more than 5 years. In addition, the embryos stored for longer than 5 years can only be used for the purpose of providing treatment.


Other Things you Should Know

Safety
Although we will do our best to ensure the safe storage of your embryos, we can not be held responsible for their safety or risk of loss of embryos due to factors outside our control, such as equipment failure. In addition, we can not guarantee that your embryos will survive the freeze-thaw process or that a successful pregnancy will result from their transfer.

Contact with the Unit
You must keep us informed of any changes in your circumstances e.g. change of address. This is because we will need to contact you in the near future to find out what you would like us to do with your embryos as they reach the end of their statutory storage period. If we are unable to contact you, your embryos will be destroyed at the end of their statutory storage period.

Remember if you have any questions or concerns regarding embryo freezing or any other aspect of your treatment, the staff at the Unit are happy to help you.